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sparsentan will lower the extent or effect of modafinil by impacting hepatic enzyme CYP2C19 metabolism. Use Caution/Keep track of. Sparsentan (a CYP2C19 inducer) decreases exposure of CYP2C19 substrates and reduces efficacy connected with these substrates.Modafinil’s suppression of Mind CYP2C9 could explain modafinil’s power to lower reactive o